Long-duration spaceflights pose unique challenges for manned missions. The effects of microgravity, including muscle atrophy and bone density loss, require meticulous countermeasures such as regular exercise and nutritional supplements. Psychological well-being is another critical concern, with astronauts experiencing isolation, confinement, and the constant threat of radiation exposure. Mission planners must design robust support systems and implement psychological protocols to ensure crew health and morale throughout extended missions.
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