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Streamlined Manufacturing Economics of pharma intermediates道場

Streamlined Manufacturing Economics of pharma intermediates道場

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学問・研究
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2025年6月1日

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iridolls (道場主)

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Bulk Synthesis: Intermediates are produced in large batches using well-established chemical reactions (e.g., catalytic hydrogenation, chiral synthesis), leveraging economies of scale to drive down unit costs.

Reduced Downstream Processing: Unlike final APIs, intermediates bypass costly purification steps (e.g., crystallization, chromatography), as their "semi-finished" state requires fewer refinements.

Global Specialization: Many intermediates are manufactured in regions with lower labor and regulatory costs (e.g., India, China), while still adhering to stringent Good Manufacturing Practices (GMP).
https://www.echemi.com/category/pharmaceutical-intermediates-c11.html

【キーワード】 pharma、intermediates

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